Gieseler H * , Kessler WJ, Finson M, Davis S, Mulhall P, Bons V, Debo D, Pikal MJ. 2007. Evaluation of Tunable Diode Laser Absorption Spectroscopy for In-Process Water Vapor Mass Flux Measurements during Freeze Drying. J Pharm Sci 96(7):1776-1793.
Category Archives: Peer Reviewed Journal Papers
Gieseler H * , Kramer T, Pikal MJ. 2007. The Use of Manometric Temperature Measurement (MTM) and SMART Freeze-Dryer Technology for Development of an Optimized Freeze-Drying Cycle. J Pharm Sci 96(12) : 3402-3418.
Gieseler H, Lee GWJ * . 2008. Effects of vial packing density on momentary freeze-drying rate of carbohydrates or a model protein measured using a microbalance technique. Pharm Res 25(2):302-312.
Schneid S, Gieseler H * . 2008. Evaluation of a New Wireless Temperature Remote Interrogation System (TEMPRIS) to Measure Product Temperature during Laboratory and Production Scale Freeze Drying. AAPS PharmSciTech 9(3):729-739.
Gieseler H, Lee GWJ * . 2008. Effect of Freeze-Dryer Design on Drying Rate of an Amorphous Protein-Formulation Determined with a Vial-Weighing Technique. Pharm Dev Technol 13(6):463-472.
Schneid S, Riegger X, Gieseler H * . 2008. Influence of Some Common Excipients on the Crystalline Modification of Freeze-Dried Mannitol. Pharm Technol, March Issue:178-184.
Gieseler H * , Kramer T, Schneid S. 2008. Quality by Design in Freeze-Drying: Cycle Design and Robustness Testing in the Laboratory Using Advanced Process Analytical Technology. Pharm Technol, October Issue: 88-95.
Meister E, Šašić S, Gieseler H * . 2009. Freeze-Dry Microscopy: Impact of Nucleation Temperature and Excipient Concentration on Collapse Temperature Data. AAPS PharmSciTech 10(3):582-588.
Meister E, Gieseler H * . 2009. Freeze-Dry Microscopy of Protein/Sugar Mixtures: Drying Behavior, Interpretation of Collapse Temperatures and a Comparison to Corresponding Glass Transition Data. J Pharm Sci 98(9):3072-3087.
Schneid S, Gieseler H * , Kessler WJ, Pikal MJ. 2009. Non-Invasive Product Temperature Determination during Primary Drying using Tunable Diode Laser Absorption Spectroscopy. J Pharm Sci 98(9):3406-3418.